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J Acupunct Res > Volume 29(6); 2012 > Article
Published online December 17, 2012.
DOI: https://doi.org/10.13045/kamms.2012087   
The Effect of Junci Medulla Herbal-acupuncture at KI10 on LPS induced Nephritis in Rats
Jee Soon Ihm, Tae Hwan Cho, Yun Kyoung Yim
Dept. of Meridian and Acupoint, College of Oriental Medicine, Daejeon University
*Corresponding author.
Yun Kyoung Yim
Tel: +82-42-280-2610   Email: docwindy@dju.krr
Objectives : This study aimed to evaluate the effects of Junci Medulla Herbal-acupuncture(JM-HA) at KI10(Umgok) on nephritis induced by lipopolysaccharide(LPS) in rats.
Methods : Rats with nephritis induced by LPS, were treated with JM-HA at KI10 3 times a week. The rats in the NP group and the saline group were treated with a needle prick and a saline injection respectively. To evaluate the effects of JM-HA at KI10 on nephritis in rats, WBC, neutrophils in blood, BUN, creatinine, TNF-α in serum, creatinine, total protein in urine and renal MPO were measured.
Results : JM-HA at KI10 significantly inhibited the increase of WBC and neutrophils in blood, BUN, creatinine, TNF-α in serum, and MPO in kidney of LPS-stimulated rats. Conclusion : JM-HA at KI10 has therapeutic effects on nephritis in LPS-stimulated rats. Therefore, it is suggested that JM-HA at KI10 may be a useful therapy in clinical field after further researches.
Keywords: nephritis, herbal-acupuncture, KI10, Junci Medulla, LPS

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