A Clinical Case Study on the Effects of Acupuncture Therapy and Ecklonia Cava Extract on Sleep Disturbances in ALS Patients※
Article information
J Korean Acupunct Moxib Soc. 2013;30(5):247-252
Publication date (electronic) : 2013 December 20
doi :
https://doi.org/10.13045/acupunct.2013064
Received 2013 November 11; Revised 2013 November 29; Accepted 2013 December 02.
Abstract
Objectives:
The purpose of this study was to observe the clinical effects of acupuncture therapy and Ecklonia cava extract on sleep disturbance in ALS patients.
Methods:
In this study one patient received acupuncture therapy and took Ecklonia cava extract. The effects of the combined administration of these treatments were evaluated using Numeric Rating Scale and Pittsburgh Sleep Quality Index.
Results:
The NRS score for sleep disturbance decreased from 10 to 1 and the PSQI score decreased from between 12∼13 to 8. After treatment, the patient stopped taking sleeping pills and antidepressant.
Conclusions:
Combined administration of acupuncture therapy and Ecklonia cava extract could be effective in improving sleep disturbances in ALS patient.
Keywords: Amyotrophic lateral sclerosis; Sleep disturbance; Numeric rating scale; Pittsburgh sleep quality index; Ecklonia cava extracts; Acupuncture
The change of sleeping time and numeric rating scale (NRS) after treatments
The scores of pittsburgh sleep quality index (PSQI) after treatments
References
1. Han TR, Bang MS. Rehabilitation medicine Seoul: Gun-ja; 2011. p. 697.
2. Kim SH. Diagnosis and Therapeutic Strategies of Amyotrophic Lateral Sclerosis. Hanyang Medical Reviews 2006;26(1):45–51.
3. Young C, Tedman BM, Williams IR. Disease Progression and Perception of Health in Patients with Motor Neuron Disease. Journal of neurological Science 1995;129(supplement):50–3.
4. Coco Daniele Lo, Mattalino Paola, Spatarol Rossella, Mattaliano Alfredo, Bella Vincenzo La. Sleep-wake Disturbances in Patients with Amyotrophic Lateral Sclerosis. Journal of Neurol Neurosurg Psychiatry 2011;82(8):839–42.
5. Kirkwood CK. Management of Insomnia. J Am Pham Assoc 1999;39(5):688–96.
6. Hong HW, Lee SD, Gam CW, Park DI. Clinical Study of Sanjoin-Tang on Insomnia Patients with Cerebrovascular Accident. The Journal of Oriental Physiology & Pathology 2004;18(6):1927–32.
7. Ryu SH, Yang DJ, Cho KH, Kim YS. The Effect of Hwangyeonhaedogtang Gamibang on Insomnia in Stroke 3 Case Report. The Journal of Oriental Medicine 2001;22(2):120–7.
8. Kim JW, Ahn DJ, Wang DJ, Lee SY, Kang HW. Clinical Study of 20 Cases of insomnia Patients with Auricular Acupuncture Therapy. The Journal of Oriental Neuropsychiatry 2004;15(1):219–30.
9. Han C, Kim JH, Ryu KJ, Ahn GS, Kwon SR. A Clinical Report on Insomnia Following Hospitalization improved by the Chuna Manual Relaxation Therapy. The Journal of Oriental Neuropsychiatry 2008;19(3):309–17.
10. Jung HH. The Effect of Psychodynamic Group Psychotherapy for Sleep problems on Depression, Anxiety, and Sleep Quality Seoul: Seoul Graduate School of Buddhism; 2005. Korean.
11. Kim MY, Cho SH, Lee SM, Jung SJ, Park KS. Eldery Sleep Pattern and Disturbing Factors Before and After Hospitalizaion. The Journal of Korean Academy of Nursing 1987;26(3):15–20.
12. Milne B. Sleep Wake Disorders and What We Can Do About Them. The Journal of Canadian Nurse 1982;78(4):24–7.
13. Fuller J, Schaller-Ayers J. Health Assessment: A Nursing Approach. Philadelphia Lippincott 2000;:52–4.
14. Kirstie NA, Andrew JB. Sleep Disturbance in Mental Health Problems and Neurodegenerative Disease. The Journal of Nature of Science of Sleep 2013;31(5):68–70.
15. The Acupuncture and Moxibustion Medicine Textbook Compilation Committee. The Acupuncture and Moxibustion 3rd 2nd Edth ed. Seoul: Jipmoondang; 2008. p. 393.
16. Le QT, Li Y, Qian ZJ, Kim MM, Kim SK. Inhibitory Effects of Polyphenols Isolated from Marine Alga Ecklonia cava on Histamine Release. Process Biochemistry 2009;44(2):168–76.
17. Kong CS, Kim JA, Yoon NY, Kim SK. Induction of Aoptosis by Phloroglucinol Derivative from Eclonia Cava in MCF-7 Human Breast Cancer Cells. Food and Chemical Toxicology 2009;47:1653–58.
18. Shin HC, Kim SH, Park YJ, Lee BH, Hwang HJ. Effects of 12-week Oral Supplementation of Ecklonia cava Polyphenols on Anthropometric and Blood Lipid Parametners in Overweight Korean Individuals: A Double-blind Randomized Clinical Trial. Phytotherapy research 2011;26(3):363–68.
19. Cho SM, Yang HJ, Jeon YJ, et al. Phlorotannins of the Edible Brown Seaweed Ecklonia cava Kjellman Induce Sleep via Positive Allosteric Modulation of Gamma aminobutyric Acid Type A-Benzodiazepine Receptor: A novel Neurological Activity of Seaweed Polyphenols. The journal of Food Chemistry 2012;132(3):1133–42.
20. Cho SM, Han DS, Kim SB, et al. Depressive Effects on the Central Nervous System and Underlying Mechanism of the Enzymatic Extract and Its Phlorotannin-Rich Fraction from Ecklonia cava Edible Brown Seaweed. Biosci Biotechnol Biochem 2012;76(1):163–8.
Article information Continued
Copyright © 2013 KAMMS. Korean Acupuncture & Moxibustion Medicine Society.